The Fluidic 983 Channel Interaction Chip by Microfluidic ChipShop enables the assessment of molecules migrating between compartments under microfluidic flow. It features 5 independent channel designs with varying dimensions and includes 3 parallel channels separated by pillar barriers in each design.
The chip displays mini Luer connection ports and is available in Zeonor and Topas.
General
This interaction chip reliably mimics physiological conditions in vitro and allows the study of cell-cell interactions, barrier penetration, and physiological responses in a more in vivo-like environment.
This chip has been developed to study cells co-cultured in three adjacent channels, into which microfluidic flows can be applied through their mini Luer ports. The three channels are divided from each other by transmissive pillar barriers. On each channel interaction chip, five independent co-culture units can be found, which differ in the width of the pillar barrier. One potential co-culture setting is the use of the two outer channels in perfusion mode, while the inner channel can be easily filled with a cell-containing gelatinous extracellular matrix, for static 3D culture conditions. However, cell culture is only one potential application area of this versatile chip.
All channels feature a depth of 500 μm. The inlets and outlets with integrated Mini Luer connections ensure leak-free junctions with the tubing and allow experiments under dynamic flow conditions.
Features
- Mini Luer connection molded with the chip: leak-free
- Highly resistant and optically clear material: Topas (COC) or Zeonor (COP)
- Standard microscope glass slide size (75.5 mm x 25.5 mm x 1.5 mm)
- 5 designs with different sizes of pillars
Content
1x Channel interaction chip with mini Luer ports
Specifications
| Reference |
CS-10001345 |
CS-10001346
|
CS-10001349 |
CS-10001350
|
CS-10001347
|
CS-10001348 |
| Lid thickness (µm) |
140 |
188 |
125 |
| Material |
Topas (COC) |
Zeonor (COP) |
PS |
| Surface Treatment |
None |
Hydrophilized |
None |
Hydrophilized |
None |
Hydrophilized |
Documentation
Click to read more information about ChipShop chips material properties.
? Channel interaction chip handling instructions
